Empore™ MiniLab
Automated System for Biological Sample Extraction & Processing
96-Well Plate
Temperature Control
Positive Pressure Filtration
Technical Specifications
Key Components
Advanced design for Minilab
1. Moving Arm
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SPE Gripper and Pipettor attachments.
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Moves X & Y directions.
2. Pipettor
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Draws, dispenses, and mixes liquids
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8-Channel.
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Retractable drip catch tray eliminates spills.
3. Gripper
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Claw action to grab plates or StageTip racks for positional control.
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Independently moves in Z direction.
4. Positive Pressure Module
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Presses down on plates or StageTip racks to apply forced air 10 – 30 PSI.
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Moves between liquid waste slot and collection slot.
5. Loading Slot
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Position to load or remove SPE plates or StageTip rack.
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StageTip adaptation in progress.
6. Sample Slot
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Position to place sample plate for transferring to SPE consumable.
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Standard 96-well collection plate.
7. Solution Reservoir
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Solution capacity of 2x 80 mL and 4x 30 mL slots.
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Removable component for refilling
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Plastic material.
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Movable cover to protect a 30 mL solution from light.
8. Tip Waste Bin
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Removable for easy pipette tip waste disposal.
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Pipettor disposes used pipette tips here.
9. Exhaust Fan
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Hose compatible for fume exhaust.
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Vents chemical vapors outside the unit.
Why Choose Empore™ MiniLab?
Automated System for Biological Sample Extraction & Processing
Unmatched Efficiency
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99% reduction in hands-on time
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2x faster for StageTips vs manual
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Total automation time: ~45 minutes for 96 samples
Proven Performance
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Consistent reproducible results
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Validated for proteomics applications
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Suitable for peptide desalting & PTM enrichment
Universal Compatibility
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Compatible with major SPE brands
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Supports 96-well plates and StageTips
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Adaptable to various protocols
Maximum Throughput
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Process 96 samples simultaneously
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100% more multitasking capability
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Reduces bottlenecks in workflow
Error Reduction
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Eliminates manual pipetting variations
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Consistent pressure and timing
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Less chance for cross-contamination
Method Flexibility
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9 modularized blocks
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Temperature-controlled heating
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Positive pressure filtration
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User-programmable methods
Intuitive Software Interface
Powerful automation control with user-friendly design
Main Tab
The main control center for your automated workflows
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Main screen for loading and running methods
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Real-time monitoring of current solution volumes
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Easy SPE format and pipette tip occupancy management
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Intuitive visual feedback during operation
See MiniLab in Action
Watch the MiniLab perform functions for SPE plate processing
Experimental Data
Quantitative results demonstrating superior reproducibility
Excellent sample-to-sample reproducibility using both 96-well plate and StageTip rack desalting.
Pearson correlation analysis of the same E. coli peptide sample desalted simultaneously in all 96-wells or 96-StageTips demonstrates exceptional consistency with averages ≥ 0.98. Repeated Pearson correlations analysis show results are consistent, validating the reliability of sample preparation for high-throughput proteomics.
Resources for MiniLab
Download technical documents and application notes
Applications
Optimized for proteomics and peptide analysis workflows
Protein/Peptide Desalting
High capacity enables small-volume desalting of peptides and proteins with excellent recovery rates exceeding 90%.
Peptide Fractionation
Efficient fractionation using ion exchange or reversed-phase chemistries for enhanced proteome coverage.
Buffer Exchange
Quick and efficient buffer exchange for downstream applications including mass spectrometry analysis.
Sample Cleanup
Remove salts, detergents, and other contaminants from biological samples before LC-MS/MS analysis.
Enrichment Applications
Selective enrichment of modified peptides including phosphopeptides and glycopeptides for PTM analysis.
Method Development
Perfect for method development when sample volumes exceed StageTip capacity but don't require full cartridge volumes.
Products Selection Guide
Choose the right sorbent chemistry for your application
Minilab Introduction