Technical Specifications
Sample Capacity
Up to 500 µL
Collection Tube
2 mL included
Pack Size
25 columns
Case Size
100 columns (4 packs)
Column Material
Low-binding PP
Binding Capacity
>300 µg peptides
Recovery
>90%
Chemical Resistance
All organic solvents
Why Choose Empore™ Spin Columns?
Pre-packed with Empore™ membrane for consistent, reproducible results
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Sample Size
Up to 500 μL per column. Spin Columns are available with 25 pcs per pack or 100 pcs per case (4 packs per case).

Reliability
Empore™ membranes evenly load samples for efficient and consistently reproducible results.
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Universal Compatibility
Use low-binding polypropylene material with chemically resistant to organic solvents and basic and acidic conditions for all protein and peptide desalting/fractionation applications.

Customizability
Choose any of our most popular membranes for your separation needs.

Frosted Area
The frosted surfaces on the collar and lid (marked by the added red borders) reduce the mess from smudging by chemicals when writing on and labeling the spin column body.

High Capacity and Recovery
Ability to bind more than 300 μg of peptides with a recovery >90%
Applications
Optimized for proteomics and peptide analysis workflows
Protein/Peptide Desalting
High capacity enables small-volume desalting of peptides and proteins with excellent recovery rates exceeding 90%.
Peptide Fractionation
Efficient fractionation using ion exchange or reversed-phase chemistries for enhanced proteome coverage.
Buffer Exchange
Quick and efficient buffer exchange for downstream applications including mass spectrometry analysis.
Sample Cleanup
Remove salts, detergents, and other contaminants from biological samples before LC-MS/MS analysis.
Enrichment Applications
Selective enrichment of modified peptides including phosphopeptides and glycopeptides for PTM analysis.
Method Development
Perfect for method development when sample volumes exceed StageTip capacity but don't require full cartridge volumes.
Products Selection Guide
Choose the right sorbent chemistry for your application

Empore™ Spin Columns
Pre-packed alternative for applications too large for StageTip processing - up to 500 µL sample capacity
Up to 500 µL Capacity
2 mL Collection Tube
>90% Recovery

Resources for Spin Coulmns
Download technical documents and application notes
Built on Empore™ Membrane SPE Technology: Empore™ Spin Columns offer a quick and easy-to-use format perfect for small-volume desalting and fractionation of peptides and proteins when StageTips are too small. Learn more about SPE technology →


