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A single disk. Endless possibilities

With a wide range of specialized membranes, including Anion, C18, C8, Cation Exchange, Chelating, SDB-XC, and Filter + C18 Sorbent Particles, each disk is engineered for precise applications, unlocking a world of potential

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Technical Specifications

Sample Capacity

Up to 500 µL

Collection Tube

2 mL included

Pack Size

25 columns

Case Size

100 columns (4 packs)

Column Material

Low-binding PP

Binding Capacity

>300 µg peptides

Recovery

>90%

Chemical Resistance

All organic solvents

Why Choose Empore™ Spin Columns?

Pre-packed with Empore™ membrane for consistent, reproducible results

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Sample Size

Up to 500 μL per column. Spin Columns are available with 25 pcs per pack or 100 pcs per case (4 packs per case).

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Reliability

Empore™ membranes evenly load samples for efficient and consistently reproducible results.

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Universal Compatibility

Use low-binding polypropylene material with chemically resistant to organic solvents and basic and acidic conditions for all protein and peptide desalting/fractionation applications.

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Customizability

Choose any of our most popular membranes for your separation needs.

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Frosted Area

The frosted surfaces on the collar and lid (marked by the added red borders) reduce the mess from smudging by chemicals when writing on and labeling the spin column body.

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High Capacity and Recovery

Ability to bind more than 300 μg of peptides with a recovery >90%

Applications

Optimized for proteomics and peptide analysis workflows

Protein/Peptide Desalting

High capacity enables small-volume desalting of peptides and proteins with excellent recovery rates exceeding 90%.

Peptide Fractionation

Efficient fractionation using ion exchange or reversed-phase chemistries for enhanced proteome coverage.

Buffer Exchange

Quick and efficient buffer exchange for downstream applications including mass spectrometry analysis.

Sample Cleanup

Remove salts, detergents, and other contaminants from biological samples before LC-MS/MS analysis.

Enrichment Applications

Selective enrichment of modified peptides including phosphopeptides and glycopeptides for PTM analysis.

Method Development

Perfect for method development when sample volumes exceed StageTip capacity but don't require full cartridge volumes.

Empore Spin Column Brochure

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Empore™ Spin Columns

Pre-packed alternative for applications too large for StageTip processing - up to 500 µL sample capacity

Up to 500 µL Capacity

2 mL Collection Tube

>90% Recovery

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Resources for Spin Coulmns

Download technical documents and application notes

Send Us a Message


Need More Information?
Let's Connect!

Our technical experts are ready to help you select the right Empore products for your specific applications and provide comprehensive support.

Built on Empore™ Membrane SPE TechnologyEmpore™ Spin Columns offer a quick and easy-to-use format perfect for small-volume desalting and fractionation of peptides and proteins when StageTips are too small. Learn more about SPE technology →

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