top of page

🔴 Originally by 3M · Now by CDS Analytical

Empore™ Particle-Loaded Membrane Technology

SPE & Proteomics Solutions

Built on 3M's patented technology, Empore™ membranes pack sorbent particles into a PTFE matrix at nanometer scale — delivering high density, uniformity, and extraction efficiency across 40+ chemistries.

​√  3M™ Patented Technology

​√  ISO 9001 · GMP Clean Room

​√  Made in the USA

​√  Specified in 13+ EPA Methods

WHY EMPORE™

Membrane technology advantages

Sorbent particles tightly enmeshed in PTFE matrix — no void space, no channeling, uniform particle distribution.

700 ml/min

Ultra-fast flow rate

47mm disk processes 1L of water in under 10 minutes at 20 inHg vacuum

Up to 1/3

Lowest elution volume

Compared to traditional loose-packed SPE — minimize or eliminate evaporation steps

10–15%

Higher consistency

Best reproducibility and lowest CVs among leading SPE products

1/10

Least particle fines

Reduces tube clogging and system downtime — extends HPLC column life

REGULATORY

Recommended in 13+ official EPA methods

Empore™ is written into EPA's official analytical methods for water quality testing. When laboratories follow these methods, Empore is the specified SPE product — making it the standard for regulatory compliance.

EPA 506

EPA 507

EPA 508.1

EPA 512.2

EPA 525.3

EPA 549.1

EPA 550.1

EPA 552.1

EPA 553

EPA 1613

EPA 1664

SW846 3535

QTM Methods

13+

EPA Methods

SORBENT CHEMISTRY

Available chemistries

Empore™ membranes are available in 40+ sorbent chemistries to match your target analytes.

Reverse Phases

C18-HD, C18-SD, C8-HD, C8-SD, C4, SDB-XC, SDB-XD, SDB-RPS, HLB, Activated Carbon, Oil & Grease, UR, 8270 sorbent

Mixed Phases

MPC, MCX, MAX, WCX, WAX

Normal Phases

NH2, PSA, CN, HILIC, Diol, and DMAE.

Ion Exchange

Cation (SCX), Anion (SAX), Chelating

Specialty

Strontium, Radium, Technetium, Cesium (radiochemical), ZrO2/C18, QuEChERS, Graphite Carbon

HD = High Density, SD = Standard Density

FORMATS

One membrane, multiple formats

The same Empore™ particle-loaded membrane — packaged in the format that fits your sample volume, throughput, and automation needs.

Disk

47mm and 90 mm — for high-volume environmental water samples

96 Well Plate

1.2 and 2.5 mL — for high-throughput processing​.

Cartridge

1, 3, and 6 mL — minimum elution volume.

StageTips

10 and 200 µL — peptide desalting & fractionation

Spin Column

500 µL — small-volume desalting

Proteomics

E-Series Technology products for advanced proteomics research.

PROTEOMICS

E-Series™ proteomics sample preparation

Complete single-vessel workflow from biological samples to LC-MS/MS-ready peptides. Under 15 minutes hands-on time. No liquid transfer, no free-bead issues.

01

Cell lysis or fixing

SDS, urea, RIPA, TFA, or methanol

02

On-filter digestion

E3 / E4 - under 15 min hands-on time

03

Desalting & fractionation

Reverse phase, ion exchange, and mixed mode

04

LC-MS/MS ready

Clean, reproducible peptides

Latest Article About Empore™ E4technology

📚 American Analytical Chemistry      •      April 2025

Simple In-Cell Processing Enables Deep Proteome Analysis of Low-Input C. elegans. Revolutionary OFIC processing approach identifies over 9,400 proteins from just 200 worms.

On-Filter In-Cell Processing

Direct protein digestion in methanol-fixed cells

9,400+

PROTEINS

200

WORMS

Single

WORM

6.4%

CV

Join Our Forum to Connect and Collaborate

Share your ideas, ask questions, and find solutions with fellow researchers

bottom of page