🔴Developed by CDS Empore™
Empore™ E-Series Technologies
Complete Proteomics Sample Preparation
E-Series integrates protein cleanup, digestion, peptide desalting, fractionation, and PTM enrichment — all in one device. Rapid, reliable, reproducible. Under 15 minutes hands-on time
⚡E2 / E3 / E4 / E5
🛡 Cell to MS-Ready
✓ Single-Cell Compatible
THE PROBLEM
Challenges in proteomics sample preparation
Costly
Current proteomics consumables are expensive, limiting adoption
High technical barrier
Current approaches require expert-level skills and extensive optimization.
Complex workflows
Easy-to-use, ready-to-go methods are needed but not available
THE SOLUTION
E-Series — a breakthrough platform for proteome science
Rapid & reliable
Under 15 minutes hands-on time. Reproducible results every time.
Scalable & automatable
Tips, filters, cartridges, and 96-well plates. From single-cell to milligram scale.
Low technical barrier
No free-bead issues. No protein-bead ratios. Designed for entry-level to expert users.
Stress-free
Single-vessel processing. No liquid transfers. No cross-contamination concerns.
CORE TECHNOLOGY
E3technology™
On-filter sample processing for general shotgun & clinical proteomics
E3technology provides equivalent qualitative and quantitative performance to currently available methods — while being significantly more economical. A powerful and versatile platform for proteome science, serving the proteomics community for 20+ years.
Efficient
Under 15 min hands-on time
Effective
Compatible with urea, SDS, RIPA, TFA, GnHCl
Economical
Bridging gaps between genomics and proteomics consumables
Robust
Zero technical barrier to entry-level biomedical scientists
Versatile
Tips, filters, cartridges, plates for different volumes & automation
Stress-free
No pH, protein-bead ratio, or cross-contamination concerns
Formats: E3tip™ (10 & 200 µL) · E3filter™ (500 µL) · E3cartridge™ (3 mL) · E3plate™ (96-well, 1.2 mL)
Low-input proteomics
E4technology™
Single-vessel, all-in-one approach for low-cell & single-cell proteomics
On-Filter In-Cell (OFIC) processing — proteins are digested directly in methanol-fixed cells. No cell lysis is required, no detergents are introduced. This single-vessel approach integrates digestion, desalting, and fractionation with minimal sample loss.
No cell lysis
Works with intact cells via methanol fixation
Single-cell capable
From individual cells to 5 million cells
Enhanced E3
Rapid and simple, ideal for low-input proteomics
Formats: E4tip™ (10 & 200 µL) · E4tip™ XL (10K–50K cells) · E4filter™ · E4cartridge™ · E4plate™
Gel-based proteomics
E2technology™
Automated in-gel digestion for cutting protein gel bands
On-Filter In-Gel (OFIG) processing with the E2 Gel-Crusher. Simply place gel bands directly into the device and centrifuge — no manual slicing into small cubes. Quick, effortless, automatable, high-recovery, and loss-free.
Automated gel crushing
No manual slicing — just centrifuge
High recovery
Loss-free, multiplexing capable
Formats: E2 Gel-Crusher
WROKFLOW
From biological samples to LC-MS/MS
Streamlined proteomics sample preparation in under 15 minutes of hands-on time.
01
Biological samples
Cells, tissues, body fluids, fungi, virus
02
Cell lysis or fixing
Buffer lysis or methanol fixation (E4)
03
On-filter digestion
E3 /4 - under 15 min hands-on time
04
Cleanup & enrichment
Empore™ membranes · E5 for PTMs
04
LC-MS/MS ready
Clean, reproducible peptides
PRODUCTS
E-Series product catalog
Popular configurations. Full catalog available in our shop.
Product | Technology | Format | Size | Capacity | Qty |
|---|---|---|---|---|---|
E3Tip™ | E3 | Pipette Tips | 10 µL | General | 25/96 |
E3tip™ | E3 | Pipette Tips | 200 µL | General | 25/96 |
E3filter™ | E3 | Spin Column | 500 µL | General | 25/100 |
E3plate™ | E3 | 96-Well Plate | 1.2 mL | General | 1/12 |
E3cartridge™ | E3 | Cartridge | 3 mL | General | 50/150 |
E4tip™ | E4 | Pipette Tips | 10 µL | 100–1K cells | 25/96 |
E4tip™ | E4 | Pipette Tips | 200 µL | 1K–10K cells | 25/96 |
E4tip™ XL | E4 | Pipette Tips | 200 µL | 10K–50K cells | 25/96 |
E4filter™ | E4 | Spin Column | 500 µL | 50K–5M cells | 25/100 |
E4cartridge™ | E4 | Cartridge | 3 mL | 50K–5M cells | 50/150 |
E4plate™ | E4 | 96-Well Plate | 1.2 mL | 50K–5M cells | 1/12 |
E2 Gel-Crusher | E2 | Gel-Crusher | -- | -- | 25/100 |