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Showing 11–17 of 17 publications

January 9, 2026

bioRxiv

C18 Disk

Targeting of the barley cell-surface receptor SRF3 by the Blumeria hordei effector AVRA13 overlaps with AVRA13 recognition by MLA and the induction of NLR-mediated cell death

Uses proximity-dependent protein labelling in transgenic barley to identify host interactomes of five AVRA effectors, discovering that AVRA13 specifically targets the receptor kinase HvSRF3 to disrupt iron homeostasis and promote fungal virulence.

Wei Shi, Merle Bilstein-Schloemer, Sara C. Stolze, et al.

February 22, 2026

bioRxiv

SDB-XC Disk

HDAC5-encoded Microprotein NISM Mediates Nucleolar Formation and Ribosomal RNA Synthesis

Discovers NISM, a 36 amino acid microprotein encoded in the HDAC5 5′-UTR, that regulates nucleolar formation and ribosomal RNA synthesis by promoting liquid-liquid phase separation of the RNA helicase DHX9.

Kevin Cao, Dat Ha, Jesse Hulahan, et al.

January 21, 2026

Advanced Science

C18 Disk

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Reveals that oncogene-driven SUMOylation suppresses HLA class-I antigen presentation by impairing immunoproteasome activity and TAP1 transport, and shows that pharmacological SUMO inhibition unmasks a targetable neoepitope repertoire to enhance cancer immunotherapy.

Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, et al.

January 7, 2026

bioRxiv

SCX Disk

Reactive Astrocytes Drive Extracellular Acidification to Mediate α-Synuclein Neurodegeneration

Identifies a mechanism by which reactive astrocytes drive neurodegeneration in Parkinson's disease and Lewy body dementia by releasing lysosomal contents that acidify the extracellular environment and activate neuronal ASIC1a channels.

Jae-Jin Song, Hyejin Park, YuRee Choi, et al.

January 1, 2026

Journal for ImmunoTherapy of Cancer, 14(1)

C18 Disk

Systematic evaluation of neoepitope predictions challenges clinically observed T-cell responses and their impact on immune evasion

Experimentally validates HLA ligand presentation of 176 predicted neoepitope-HLA combinations, finding only 22% are successfully presented, with significant implications for cancer vaccine design and immune evasion studies.

Badeel Kh Q Zaghla, Zuhal Safyürek, Daniela Gröger, et al.

January 20, 2026

Proteomes

SDB Disk

Cross-Species Analysis of ABA-Induced Phosphosignaling Landscapes in Rice, Soybean, and Arabidopsis

Comparative phosphoproteomic study examining abscisic acid signaling across three major crop species to identify conserved and divergent phosphorylation networks involved in drought stress responses.

Hinano Takase, Sotaro Katagiri, Takuma Ide, et al.

April 2, 2026

International Journal of Food Microbiology

C18 Disk

Strain-specific effects of bacterial proteolytic activity on acid and rennet coagulation of milk

Investigates how strain-specific proteolytic activity of Pseudomonas bacteria affects milk coagulation properties, using proteomics to characterize protein degradation patterns relevant to dairy processing.

Veronica Moscone, Davide Porcellato, et al.

  • Page 2

Showing 11–17 of 17 publications

January 9, 2026

bioRxiv

C18 Disk

Targeting of the barley cell-surface receptor SRF3 by the Blumeria hordei effector AVRA13 overlaps with AVRA13 recognition by MLA and the induction of NLR-mediated cell death

Uses proximity-dependent protein labelling in transgenic barley to identify host interactomes of five AVRA effectors, discovering that AVRA13 specifically targets the receptor kinase HvSRF3 to disrupt iron homeostasis and promote fungal virulence.

Wei Shi, Merle Bilstein-Schloemer, Sara C. Stolze, et al.

February 22, 2026

bioRxiv

SDB-XC Disk

HDAC5-encoded Microprotein NISM Mediates Nucleolar Formation and Ribosomal RNA Synthesis

Discovers NISM, a 36 amino acid microprotein encoded in the HDAC5 5′-UTR, that regulates nucleolar formation and ribosomal RNA synthesis by promoting liquid-liquid phase separation of the RNA helicase DHX9.

Kevin Cao, Dat Ha, Jesse Hulahan, et al.

January 21, 2026

Advanced Science

C18 Disk

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Reveals that oncogene-driven SUMOylation suppresses HLA class-I antigen presentation by impairing immunoproteasome activity and TAP1 transport, and shows that pharmacological SUMO inhibition unmasks a targetable neoepitope repertoire to enhance cancer immunotherapy.

Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, et al.

January 7, 2026

bioRxiv

SCX Disk

Reactive Astrocytes Drive Extracellular Acidification to Mediate α-Synuclein Neurodegeneration

Identifies a mechanism by which reactive astrocytes drive neurodegeneration in Parkinson's disease and Lewy body dementia by releasing lysosomal contents that acidify the extracellular environment and activate neuronal ASIC1a channels.

Jae-Jin Song, Hyejin Park, YuRee Choi, et al.

January 1, 2026

Journal for ImmunoTherapy of Cancer, 14(1)

C18 Disk

Systematic evaluation of neoepitope predictions challenges clinically observed T-cell responses and their impact on immune evasion

Experimentally validates HLA ligand presentation of 176 predicted neoepitope-HLA combinations, finding only 22% are successfully presented, with significant implications for cancer vaccine design and immune evasion studies.

Badeel Kh Q Zaghla, Zuhal Safyürek, Daniela Gröger, et al.

January 20, 2026

Proteomes

SDB Disk

Cross-Species Analysis of ABA-Induced Phosphosignaling Landscapes in Rice, Soybean, and Arabidopsis

Comparative phosphoproteomic study examining abscisic acid signaling across three major crop species to identify conserved and divergent phosphorylation networks involved in drought stress responses.

Hinano Takase, Sotaro Katagiri, Takuma Ide, et al.

April 2, 2026

International Journal of Food Microbiology

C18 Disk

Strain-specific effects of bacterial proteolytic activity on acid and rennet coagulation of milk

Investigates how strain-specific proteolytic activity of Pseudomonas bacteria affects milk coagulation properties, using proteomics to characterize protein degradation patterns relevant to dairy processing.

Veronica Moscone, Davide Porcellato, et al.

  • Page 2
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