Why Choose Empore™ Cartridges?
Combining Empore™ membrane technology with innovative cartridge design
Minimal Elution Volumes
Small bed volume design allows elution with as little as 100-200 µL for 1mL cartridges, eliminating evaporation steps and reducing total solvent usage. Perfect for LC-MS/MS analysis.
Prefilter Protection
Graded density polypropylene prefilter with multiple layers prevents clogging from biological samples, ensuring consistent flow rates and extending membrane life.
Versatile Compatibility
Standard luer design fits all common SPE manifolds and automated systems. Compatible with centrifugation, vacuum, and positive pressure processing methods.
Superior Reproducibility
Densely packed Empore™ membrane eliminates channeling effects, providing consistent extraction efficiency and reducing method development time.
Technical Specifications
Membrane Diameter
5.5 mm
Well Volume
1.2 or 2.5 mL
Membrane Thickness
0.75 mm
Bed Volume
18 μL
Plate Format
Standard 96-well
Plate Dimensions
ANSI/SLAS Standard
Membrane Composition
≥90% sorbent particles
Prefilter
Graded Density PP
Applications
Proven performance across diverse analytical challenges
Pharmaceutical Analysis
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Drug metabolite extraction
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Bioanalytical method development
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Pharmacokinetic studies
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Formulation analysis
Biological Samples
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Serum and plasma cleanup
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Urine sample preparation
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Protein precipitation follow-up
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Phospholipid removal
Life Sciences
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Biomarker analysis
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Metabolomics studies
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Vitamin extraction
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Hormone analysis
Clinical Research
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Therapeutic drug monitoring
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Toxicology screening
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Endogenous compound analysis
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Clinical trial support
Environmental
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Water quality testing
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Pesticide residue analysis
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Emerging contaminants
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PFAS extraction
Food & Beverage
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Mycotoxin analysis
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Veterinary drug residues
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Natural product extraction
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Flavor compound isolation
Cartridge Selection Guide
Choose the optimal size for your sample volume and application
1 mL
4mm diameter
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Sample volume: 0.05-0.5 mL
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Elution volume: 100-200 µL
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Ideal for miniaturized SPE
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Fast automation throughput
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Centrifugation recommended
3 mL
7mm diameter
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Sample volume: 0.5-2 mL
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Elution volume: 200-400 µL
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Most versatile size
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Automation compatible
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Replaces 100mg/1mL columns
6 mL
10mm diameter
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Sample volume: Several mL
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Elution volume: 600-1000 µL
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Higher capacity
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Faster flow rates
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Ideal for complex matrices
Products Selection Guide
Choose the right sorbent chemistry for your application
Membrane Type | Size | Package (PCS/Case) | Price ($) | Part Number | Description |
|---|---|---|---|---|---|
Anion | 1mL | 100 | 202.74 | 98-0604-0501-0EA | 4152HD EDC ANION-SR 1mL |
Anion | 1mL | 300 | 608.21 | 98-0604-0501-0 | 4152HD EDC ANION-SR 1mL |
Anion | 3mL | 50 | 173.22 | 98-0604-0502-8EA | 4252HD EDC ANION-SR 3mL |
Anion | 3mL | 150 | 519.66 | 98-0604-0502-8 | 4252HD EDC ANION-SR 3mL |
Anion | 6mL | 30 | 176.45 | 98-0604-0503-6EA | 4352HD EDC ANION-SR 6mL |
Anion | 6mL | 90 | 529.35 | 98-0604-0503-6 | 4352HD EDC ANION-SR 6mL |
Anion 2 layer | 3mL | 50 | 192.28 | 98-0604-0511-3EA | 4252HD2 EDC ANION-SR 3mL, 2-layer |
Anion 2 layer | 3mL | 150 | 576.83 | 98-0604-0511-3 | 4252HD2 EDC ANION-SR 3mL, 2-layer |
Anion 2 layer | 6mL | 30 | 230.11 | 98-0604-0504-4EA | 4352HD2 EDC ANION-SR 6mL, 2-layer |
Anion 2 layer | 6mL | 90 | 690.33 | 98-0604-0504-4 | 4352HD2 EDC ANION-SR 6mL, 2-layer |
C18/Alumina | 6mL | 30 | 125.42 | 98-0604-0160-1EA | 4361SD EDC C18/Alumina 6mL |
C18/Alumina | 6mL | 90 | 376.26 | 98-0604-0160-1 | 4361SD EDC C18/Alumina 6mL |

Empore™ Cartridges
Miniaturized SPE solution with proprietary prefilter technology for biological and complex samples
1mL, 3mL, 6mL Formats
Prefilter Protection
Low Elution Volumes

Resources for Cartridges
Download technical documents and application notes
Built on Empore™ Membrane SPE Technology: Multi-layer polypropylene prefilter prevents particulates and macromolecules from clogging the membrane, ensuring optimal flow rates for biological samples including serum and plasma. Learn more about SPE technology →


